Resistant Starch from High-Amylose Maize Increases Insulin Sensitivity in Overweight and Obese Men


Release time:

2023-07-03

This study evaluated the effects of 2 levels of intake of high-amylose maize type 2 resistant starch (HAM-RS2) on insulin sensitivity (SI) in participants with waist circumference≥89 (women) or≥102 cm (men). Participants received 0 (control starch), 15, or 30 g/d (double-blind) of HAM-RS2 in random order for 4-wk periods separated by 3-wk washouts.

The results of this study indicate that consumption of 15–30 g/d of HAM-RS2 improved SI in overweight and obese men. The improvement in SI relative to control is consistent with data from other studies of HAM-RS2 conducted in men and women in short-term and longer-term feeding trials . However, the present study is the first to our knowledge to show such improvements in SI at a level of intake as low as 15 g/d HAM-RS2. A previous study did not show an effect following intakes of 12 g/d HAM-RS2 for 6 wk; however, HOMA%S was used as an indicator of SI, which is less sensitive compared to the method used in the present study . The magnitude of the increase in SI in men is similar to that observed with weight loss of ~10% of body weight in obese individuals.

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